ThermaLift-47 - At a glance

ThermiLift-47 is an AI-designed biomimetic peptide that mimics the skin lifting and firming effects of radiofrequency (RF) treatments by stimulating Heat Shock Protein-47 (HSP-47), improving collagen quality, skin elasticity and wrinkle appearance without thermal stress.

Claims
  • Anti Ageing
  • Anti Wrinkle
  • Barrier Repair
  • Firming
  • Healing
  • Hydrating
  • Lifting
  • Moisturising
  • Radiance
  • Regenerating
  • Revitalising
  • Sensitive skin
Functions
  • Cosmetic Ingredient
  • Active
  • Peptides
Estimated Lead Time:
4-6 Weeks
Shelf Life:
2 years
Usage Level:
1 - 3%
Country of Origin:
United Kingdom
Download Datasheet
Download MSDS

The detail on ThermaLift-47
from INCOSPHARM CORPORATION

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ThermiLift-47 is a next-generation anti-ageing peptide developed using Incospharm’s AI-powered AMPed® (AI-Maneuvered Peptidomimetics Design) platform. Designed as a biohacking cosmetic ingredient, it reproduces the biological benefits of professional radiofrequency (RF) skin tightening treatments without exposing the skin to heat.

Unlike conventional collagen-boosting ingredients, ThermiLift-47 targets Heat Shock Protein-47 (HSP-47), a specialised molecular chaperone responsible for correct collagen folding and structural stability. By increasing HSP-47 expression, the peptide enhances collagen maturation, strengthens the dermal matrix, improves elasticity and visibly reduces wrinkles while supporting overall skin firmness and lifting.

Clinical evaluation demonstrated significant improvements in facial lifting and skin elasticity after just two weeks of use, with even greater lifting benefits when combined with at-home RF beauty devices. This makes ThermiLift-47 an ideal active for premium anti-ageing skincare, firming serums, lifting creams, neck treatments and formulations designed to complement beauty devices. The technology is protected by a Korean patent and developed using advanced AI peptide discovery methods

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